Genicular Artery Embolization (GAE)

A Minimally Invasive Treatment for Knee Osteoarthritis

About the Procedure

GAE is a catheter-based, minimally invasive procedurethat blocks abnormal blood vessels driving inflammation in knee osteoarthritis.

- Outpatient procedure – same-day discharge
- Tiny puncture, no large incision
- Preserves future surgical options

Ideal Patient Candidates

Symptomatic knee osteoarthritis

If you have ongoing knee pain, stiffness, or swelling caused by osteoarthritis — especially pain that worsens with walking, climbing stairs, or standing for long periods — you may be a good candidate for GAE. This treatment targets the small blood vessels that contribute to inflammation in arthritic knees, helping reduce pain and improve mobility.

Failed conservative care (NSAIDs, physical therapy, or injections)

GAE is typically recommended for patients who have already tried standard non-surgical treatments — such as anti-inflammatory medications, physical therapy, or corticosteroid/hyaluronic acid injections — but continue to experience pain or limited function. It’s a next-step option before considering surgery.

Not ready, not medically fit, or unwilling to undergo joint replacement

For some individuals, knee replacement surgery may not be suitable due to medical conditions, age, or personal preference. GAE offers a minimally invasive, outpatient alternative that can provide meaningful pain relief and improved function without the risks or recovery time associated with surgery

Clinical Benefits

1. Pain relief within weeks

2. Improved function and mobility

3. Durable results in multiple clinical studies

4. Low complication rate

  • Most patients experience significant reduction in knee pain within 2–6 weeks after the procedure.
  • Clinical trials report average pain score reductions of 50–70% on standardized pain scales (VAS/WOMAC).
  • Patients often regain improved range of motion and daily activity function within 1–3 months.
  • Enhanced walking distance and ability to perform weight-bearing activities are frequently reported.
  • Sustained pain relief and improved function have been documented up to 24–36 months post-procedure.
  • Studies from the U.S., Japan, and Europe confirm consistent outcomes with repeated follow-up imaging showing decreased synovial hypervascularity.
  • Reported adverse event rate is <1–2%, typically minor (e.g., transient skin discoloration or mild post-procedural pain).
  • No significant risk of osteonecrosis or joint damage observed in long-term follow-up studies.

How to Refer

Discover if Genicular Artery Embolization is right for you.

If knee pain is limiting your life and traditional treatments haven’t helped, a consultation can help determine whether GAE is a safe and effective option for your condition.
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